Small molecule analysis

Analysis of small molecules is performed at all sites in the SwedNMR network but are a main focus in term of user support in Gothenburg, Umeå and Uppsala. Small molecule analysis covers a wide array of applications, from structure determination of of natural product, dynamics, fragment-based screening (FBS) and other interaction studies between small and large molecules. We support users from both academia and industry and welcome projects in all small molecule applications.

University of Gothenburg

Contact person: Someone

E-mail: someone@nmr.gu.se

For more information: https://www.gu.se/en/nmr/research-areas/small-molecule-nmr

Umeå University

At Umeå University, one of our focus areas is fragment-based screening (FBS) using a 600 MHz spectrometer with a cooled SampleJet and liquid handling systems for sample preparation. Two different fragment libraries are available in-house, one general purpose library consisting of 800 fragments and a smaller, fluorinated library consisting of 460 fragments. We also have experience with general protein-ligand interaction studies, non-standard nuclei in both solution- and solid-state, and structure determination of small organic molecules and peptides. We also have a unique setup for deuerium isotopomer studies with a 2H-observe DUX cryo-probe.