Analysis of small molecules is performed at all sites in the SwedNMR network but are a main focus in term of user support in Gothenburg, Umeå and Uppsala. Small molecule analysis covers a wide array of applications, from structure determination of of natural productproducts, dynamics, fragment-based screening (FBS) and other interaction studies between small and large molecules. We support users from both academia and industry and welcome projects in all small molecule applications.
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The Swedish NMR Centre at the University of Gothenburg have has setups for acquisition of 1H, 13C, 15N, 31P and 19F spectra for organic molecules using cryogenically cooled probes (at 600 - 900 MHz) with great sensitivity, with one instrument specifically dedicated to 13C-detected experiments. We also have a BBO probe at 600 MHz for non-routine nuclei (e.g. 11B).
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For more information: https://www.umu.se/en/research/infrastructure/nmr/
Uppsala University
The NMR center at Uppsala University is equipped with two Bruker Avance Neo spectrometers (500 and 600 MHz) equipped with TXO and TCI cryo-probes, and two Varian MR400-DD2 spectrometers using OneNMR probes (broadband).
In addition to routine 1H, 13C, 31P, 15N, and 19F NMR experiments, spectra involving uncommon heteronuclei, for example, 11B, 7Li, 23Na, and 29Si NMR can be acquired. Besides standard bio- and small molecule NMR experiments, our equipment allows for variable temperature (-40 ºC to 80 ºC for 500 and 600 MHz and -80 ºC to 130 ºC for 400 MHz) studies. We have expertise in structure elucidation, natural product and peptide NMR, diffusion, interaction studies, paramagnetic NMR, etc.
Contact person: Mate ErdelyiRuisheng Xiong
E-mail: mate.erdelyi@kemi nmruppsala@kemi.uu.se
For more information: NMR Uppsala - Nuclear Magnetic Resonance Center Uppsala
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