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Day 1
13.15 – 14.00: Welcome, introduction and initial round table discussion about the participants aim for the meeting
14.00 – 15.00: How quantitative is an HSQC? (Benjamin Goerling)
15.00 – 15.30: Coffee break
15.30 – 16.30: Moderated discussion/round table
ca 19:00 Meeting dinner
Day 2
09.00 – 10.00: Title to be announced Towards robust quantitative 2D HSQC NMR with high precision and sensitivity (Gérald Remaud)
10.00 – 10.30: Coffee break
10.30 – 11.30: Moderated discussion/round table
11.30 – 12.00: Closing
Suggested literature to read before the meeting
Heikkinen S, Toikka MM, Karhunen PT, Kilpeläinen IA. Quantitative 2D HSQC (Q-HSQC) via suppression of J-dependence of polarization transfer in NMR spectroscopy: application to wood lignin. J Am Chem Soc. 2003,125(14), 4362-7.
Hu K, Westler WM, Markley JL. Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)). J Am Chem Soc. 2011, 133(6),1662-5.
Haddad L, Renou S, Remaud GS, Rizk T, Bejjani J, Akoka S. A precise and rapid isotopomic analysis of small quantities of cholesterol at natural abundance by optimized 1H-13C 2D NMR. Anal Bioanal Chem., 2021, 413(6), 1521-1532.
Giraudeau P. Quantitative NMR spectroscopy of complex mixtures. Chemical Communications (Cambridge, England), 2023, 59(44), 6627-6642.
Lane D, Skinner TE, Gershenzon NI, Bermel W, Soong R, Dutta Majumdar R, Liaghati Mobarhan Y, Schmidt S, Heumann H, Monette M, Simpson MJ, Simpson AJ. Assessing the potential of quantitative 2D HSQC NMR in 13C enriched living organisms. J Biomol NMR, 2019, 73(1-2), 31-42.
Castañar L, Parella T. Recent Advances in Small Molecule NMR: Improved HSQC and HSQMBC Experiments. Annual Reports on NMR Spectroscopy, 2015, 84, 163-232.